The scientific advisory committee identified four key areas of research that will define APERSU’s research agenda.
- Applications of PROMs in clinical practice (e.g., decision aids, patient engagement, patient management, decision making, patients and clinicians perspective, clinical and cost effectiveness of PROMs)
- Applications of PROMs in health systems (e.g., routine outcome measurement, quality management, quality improvement and performance, international comparisons)
- Understanding of PROMs scores (e.g., minimal clinical important difference, measurement properties, comparisons across PROMs measures)
- Enhancing the quality of PROMs Use (e.g., methods of data collection and presentation, methods of repeated measurements, usefulness of PROMs in special groups, response shift, case mix adjustment, knowledge transfer, translation, and utilization)
Properties of the EQ-5D-5L in the Canadian Population: Minimal Important Difference and Comparative Performance with other Measures in Large Scale Health Applications: This program of research has two general aims: 1) to compare the measurement properties of the EQ-5D instruments (3- and 5-level) with other generic and disease-specific measures of health status and health-related quality of life, with particular attention to the individual dimensions of the EQ-5D; and 2) to generate estimates for a minimal important difference (MID) for the EQ-5D-5L index score.
Evaluation of routinely Measured PATient reported outcomes in HemodialYsis care (“EMPATHY”) Trial: This project aims to determine the effects of routine measurement and reporting to care providers of patient-reported outcome measures (PROMs) namely the modified Edmonton Symptom Assessment Scale – renal (mESASr) and/or the EQ-5D-5L on patient reported experience, particularly patient-clinician communication, for patients with chronic kidney disease (CKD) undergoing hemodialysis. The EMPATHY Trial will be a large, multi-center cluster randomized trial, involving up to 80 dialysis units in Ontario, Alberta and BC. The EMPATHY Trial is one project under the umbrella of a large, pan-Canadian research network known as CAN-SOLVE CKD.
The use and measurement properties of EQ-5D in vulnerable populations: A systematic review of the literature: The objective of this review is to identify, summarize and appraise the literature on the use and measurement properties of EQ-5D instruments in socially vulnerable populations, i.e. populations who are at risk of adverse health outcomes due to the socioeconomic environment and resources; including but not limited to homelessness, substance abuse among others.
PROMs in Primary Care Networks in Alberta: An end-user perspective: APERSU’s team collaborated with the Primary Care Measurement Capacity Initiative (MCI) group led by Dr. Scott Oddie with Alberta Health Services, on a project that explored the use of PROMs in primary care networks (PCNs) in Alberta, and identified the facilitators and barriers to PROMs implementation in this setting.
This program aims to encourage a new generation of talented young researchers to pursue research and careers in health status measurement and health services research. Interns receive invaluable, direct experience working on specific projects under the guidance of academic members during the summer months (between May and August).
- Katelynn Crick, PhD candidate, University of Alberta
- Shelby Hoffman, MPH student, University of Saskatchewan
- Andrews Tawiah, PhD student, University of Alberta
- Tahmid Kashem, MPH student, University of Alberta
Al Sayah, Xie F, Qiu W, Johnson JA. Comparative Performance of the EQ-5D-5L and SF-6D in Adults with Type 2 Diabetes. Quality of life Research (forthcoming). Al Sayah F, Johnson JA, Ohinmaa A, Xie F, Bansback N. Health literacy and logical inconsistencies in health state valuations: Results from the Canadian EQ-5D-5L valuation study. Quality of life Research 2017; 26(6):1483-92. McClure N, Al Sayah F, Xie F, Luo N, Johnson JA. Instrument-defined estimates of minimally important difference in EQ-5D-5L index score for Canadian, Chinese and Spanish scoring algorithms. Value in Health 2017; 20(4):644-650. Al Sayah F, Johnson ST, Vallance J. Health Literacy, Pedometer, and Self-Reported Walking Among Older Adults. American Journal of Public Health 2016; 106(2):327-33. Al Sayah F, Bansback N, Bryan S, Ohinmaa A, Pullenayegum E, Poissant L, Xie F, Johnson JA. Determinants of Health Preferences in the Canadian EQ-5D-5L Valuation Study. Quality of life Research 2016 Jul;25(7):1679-85.
International Society for Pharmacoeconomics and Outcomes Research, 22nd Annual International Meeting, May 20-24, 2017. 38th Annual North American Society for Medical Decision Meeting (SMDM), October 23-26, 2016. ISOQOL 23rd Annual Conference, Copenhagen, Denmark, October 19-22, 2016. 33rd EuroQol Plenary Meeting, Berlin Sept 15-17, 2016. ISOQOL 22nd Annual Conference, Vancouver, Canada, October 21-24, 2015.
APERSU collaborates with researchers from several academic institutions across Canada and internationally:
- Nancy Devlin, Office of Health Economics, UK
- Mike Herdman, Office of Health Economics, UK
- Michael Walsh, McMaster University, Hamilton, Ontario
- Feng Xie, McMaster University, Hamilton, Ontario
- Nan Luo, National University of Singapore, Singapore
- Braden Manns, University of Calgary, Calgary, Alberta
- Nick Bansback, University of British Columbia, Vancouver, British Columbia
- Deborah Marshall, University of Calgary, Calgary, Alberta
- Scott Oddie, AHS and Red Deer College, Red Deer, Alberta
- Bas Janssen, The EuroQol Group, Netherlands
- David Whitehurst, Simon Fraser University, Vancouver, British Columbia