APERSU Research Agenda
- Applications of PROMs in clinical practice (e.g., decision aids, patient engagement, patient management, decision making, patients and clinicians perspective, clinical and cost effectiveness of PROMs)
- Applications of PROMs in health systems (e.g., routine outcome measurement, quality management, quality improvement and performance, international comparisons)
- Understanding of PROMs scores (e.g., minimal clinical important difference, measurement properties, comparisons across PROMs measures)
- Enhancing the quality of PROMs Use (e.g., methods of data collection and presentation, methods of repeated measurements, usefulness of PROMs in special groups, response shift, case mix adjustment, knowledge transfer, translation, and utilization)
Current Projects
Properties of the EQ-5D-5L in the Canadian Population: Minimal Important Difference and Comparative Performance with other Measures in Large Scale Health Applications:
This program of research has two general aims: 1) to compare the measurement properties of the EQ-5D instruments (3- and 5-level) with other generic and disease-specific measures of health status and health-related quality of life, with particular attention to the individual dimensions of the EQ-5D; and 2) to generate estimates for a minimal important difference (MID) for the EQ-5D-5L index score.
Evaluation of routinely Measured PATient reported outcomes in HemodialYsis care (“EMPATHY”) Trial: This project aims to determine the effects of routine measurement and reporting to care providers of patient-reported outcome measures (PROMs) namely the modified Edmonton Symptom Assessment Scale – renal (mESASr) and/or the EQ-5D-5L on patient reported experience, particularly patient-clinician communication, for patients with chronic kidney disease (CKD) undergoing hemodialysis. The EMPATHY Trial will be a large, multi-center cluster randomized trial, involving up to 80 dialysis units in Ontario, Alberta and BC. The EMPATHY Trial is one project under the umbrella of a large, pan-Canadian research network known as CAN-SOLVE CKD.
The use and measurement properties of EQ-5D in vulnerable populations: A systematic review of the literature: The objective of this review is to identify, summarize and appraise the literature on the use and measurement properties of EQ-5D instruments in socially vulnerable populations, i.e. populations who are at risk of adverse health outcomes due to the socioeconomic environment and resources; including but not limited to homelessness, substance abuse among others.
PROMs in Primary Care Networks in Alberta: An end-user perspective: APERSU’s team collaborated with the Primary Care Measurement Capacity Initiative (MCI) group led by Dr. Scott Oddie with Alberta Health Services, on a project that explored the use of PROMs in primary care networks (PCNs) in Alberta, and identified the facilitators and barriers to PROMs implementation in this setting.The scientific advisory committee identified four key areas of research that will define APERSU’s research agenda.
- Applications of PROMs in clinical practice (e.g., decision aids, patient engagement, patient management, decision making, patients and clinicians perspective, clinical and cost effectiveness of PROMs)
- Applications of PROMs in health systems (e.g., routine outcome measurement, quality management, quality improvement and performance, international comparisons)
- Understanding of PROMs scores (e.g., minimal clinical important difference, measurement properties, comparisons across PROMs measures)
- Enhancing the quality of PROMs Use (e.g., methods of data collection and presentation, methods of repeated measurements, usefulness of PROMs in special groups, response shift, case mix adjustment, knowledge transfer, translation, and utilization)
EuroQol Data for Assessment of Population Health Needs and Instrument Evaluation (EQ-DAPHNIE): The overall aim of the EQ-DAPHNIE project is to create research infrastructure for the EuroQol Group that would support future research projects which have specific research objectives/questions. The breadth of potential research topics would be characterized under two broad domains: 1) Population health status (e.g., develop country-specific population norms, social determinants of health and population health inequities); 2) Comparative performance and validation of instruments (e.g., EQ-HWB vs. EQ-5D-5L).
Why measure HRQL?
Click here to learn about health-related quality of life.
Minimally Important Difference (MID) of the EQ-5D-5L Index Score
Click here to learn about hte minimally important difference of the EQ-5D-5L index score and how it can be used.
What is a QALY?
Click here to learn about a Quality Adjusted Life Year (QALY).
The impact of the COVID-19 pandemic on health-related quality of life in Alberta
In collaboration with the Health Quality Council of Alberta, the APERSU research team examined the impact of the COVID-19 pandemic on health-related quality of life in adult patients seeking primary care or emergency department services in the province. Click on the infographics to learn more.
Summer Internships
This program aims to encourage a new generation of talented young researchers to pursue research and careers in health status measurement and health services research. Interns receive invaluable, direct experience working on specific projects under the guidance of academic members during the summer months (between May and August).
2019 INTERNS
- Simrat Sandha, MPH student, University of Alberta
- Kai Erh Kao, MSc student, University of Alberta
2018 INTERNS
- Maryna Derkach, PhD student, University of Alberta
- Shahela Laboni, MSc student, University of Alberta
2017 INTERNS
- Andrews Tawiah, PhD student, University of Alberta
- Tahmid Kashem, MPH student, University of Alberta
2016 INTERNS
- Katelynn Crick, PhD candidate, University of Alberta
- Shelby Hoffman, MPH student, University of Saskatchewan
Visiting Students
- 2019 Olivia Ernstsson, Karolinska Institutet
- 2021 Vivian Nystrom, University of Oslo
- 2022 Ana Claudia Fuhrmann, Federal University of Rio Grande do Sul
Publications
2022
- Schick-Makaroff K., Wozniak L.A., Short H., Davison S.N., Klarenbach S., Buzinski R., Walsh M., Johnson J.A. How the Routine Use of Patient-Reported Outcome Measures for Hemodialysis Care Influences Patient-Clinician Communication CJASN Nov 2022, 17 (11) 1631-1645; DOI: 10.2215/CJN.05940522
- Elliott M, Baragar B, Schick-Makaroff K, Manns B, Love S, Donald M, Santana M, Corradetti B, Finlay J, Johnson JA, Walsh M. “You need a team” – Perspectives on interdisciplinary symptom management using patient-reported outcome measures in hemodialysis care: A qualitative study. J Patient Rep Outcomes2022 (forthcoming).
- Derkach M, Al Sayah F, Ohinmaa A, Svenson LW, Johnson JA. Comparative Performance of the EuroQol EQ-5D-5L and the CDC Healthy Days Measures in Assessing Population Health. J Patient Rep Outcomes. 2022;6(1):64. Published 2022 Jun 13. doi:10.1186/s41687-022-00474-7
- Al Sayah F, Lahtinen M, Simon R, Higgins B, Ohinmaa A, Johnson JA. The impact of COVID-19 pandemic on health-related quality of life of adults visiting emergency departments and primary care settings in Alberta. Can J Public Health. 2022 Feb;113(1):96-106.PMID: 35015286.
- McClure N, Xie F, Paulden M, Ohinmaa A, Johnson J. Small differences in EQ-5D-5L health utility scores were interpreted differently between and within respondents. Journal of Clinical Epidemiology 2022; 142:Feb 01:133-143. PMID: 34737062.
- Wen J, Jin X, Al Sayah F, Short H, Ohinmaa A, Davison SN, Walsh M, Johnson JA. Mapping the Edmonton Symptom Assessment System-Revised: Renal to the EQ-5D-5L in patients with chronic kidney disease. Qual Life Res. 2021 Jul 19. doi: 10.1007/s11136-021-02948-5. PMID: 34278540
- Wen J, Jin X, Al Sayah F, Johnson JA, Paulden M, Ohinmaa A. Economic evaluation on sucrose octasulfate dressing for treating patients with diabetic foot ulcers in Canada. Canadian Journal of Diabetes. 2021 Jul 9:S1499-2671(21)00193-3. doi: 10.1016/j.jcjd.2021.07.001. Epub ahead of print. PMID: 35148951.
2021
- Wen J, Jin X, Al Sayah F, Short H, Ohinmaa A, Davison SN, Walsh M, Johnson JA. Mapping the Edmonton Symptom Assessment System-Revised: Renal to the EQ-5D-5L in patients with chronic kidney disease. Qual Life Res. 2021 Jul 19. doi: 10.1007/s11136-021-02948-5. .PMID: 34278540
- Al Sayah F, McAlister FA, Ohinmaa A, Majumdar SR, Johnson JA. The predictive ability of EQ-5D-3L compared to the LACE index and its association with 30-day post-hospitalization outcomes. Qual Life Research 2021 (epub ahead of print) DOI: 10.1007/s11136-021-02835-z. PMID: 33974221.
- McClure NS, Paulden M, Ohinmaa A, Johnson JA. Modifying the quality-adjusted life year calculation to account for meaningful change in health-related quality of life: insights from a pragmatic clinical trial. European Journal of Health Economics 2021 (epub ahead of print). DOI: 10.1007/s10198-021-01324-x. PMID: 34089409.
- Short H, Al Sayah F, Ohinmaa A, Johnson JA. The performance of the EQ-5D-3L in screening for anxiety and depressive symptoms in hospital and community settings. Health Qual Life Outcomes 2021;19(1):96. PMID: 33741011.
- Chemli J, Drira C, Felfel H, Roudijk B, Al Sayah F, Kouki M, Kooli A, Razgallah Khrouf M. Valuing health-related quality of life using a hybrid approach: Tunisian value set for the EQ-5D-3L. Qual Life Res. 2021 May;30(5):1445-1455. doi: 10.1007/s11136-020-02730-z. Epub 2021 Jan 14. PMID: 33447958; PMCID: PMC8068700.
- Schick-Makaroff, K., Wozniak, L. A., Short, H., Davison, S. N., Klarenbach, S., Buzinski, R., Walsh, M., & Johnson, J. A. (2021). Burden of mental health symptoms and perceptions of their management in in-centre hemodialysis care: a mixed methods study. Journal of patient-reported outcomes, 5(1), 111. https://doi.org/10.1186/s41687-021-00385-z. PMID: 34709470.
- Wu Xiuyun, Veugelers P, Ohinmaa A. Health behaviour, health-related quality of life, and mental health among Canadian children: a population-based cohort study. Frontiers in Nutrition 2021; 8:638259; 1-11. doi: 10.3389/fnut.2021.638259 (IF 3.365). PMID: 33777992.
- Saravana-Bawan B, Warkentin L, Ohinmaa A, Wagg A, Padwal R, Clement F, Holroyd-Leduc J, Khadaroo R. Patients reported outcomes in an elder-friendly surgical environment: Prospective, controlled before-after study. Annals of Medicine and Surgery 2021; 65: May: 102368: 1-6. PMID: 34026101.
APERSU team authorship in the JPRO supplement:
- Dean S, Al Sayah F, Johnson JA. Measuring value in healthcare from a patients’ perspective. J Patient Rep Outcomes 2021;5(Suppl 2):88. PMID: 34637001.
- Al Sayah F, Lahtinen M, Bonsel GJ, Ohinmaa A, Johnson JA. A multi-level approach for the use of routinely collected patient-reported outcome measures (PROMs) data in healthcare systems. J Patient Rep Outcomes 2021;5(Suppl 2):98. PMID: 34637031.
- Al Sayah F, Jin X, Johnson JA. Selection of patient-reported outcome measures (PROMs) for use in health systems. J Patient Rep Outcomes 2021;5(Suppl 2):99. PMID: 34637010.
- Davison SN, Klarenbach S, Manns B, Schick-Makaroff K, Buzinski R, Corradetti B, Short H, Johnson JA. Patient-reported outcome measures in the care of in-centre hemodialysis patients. J Patient Rep Outcomes 2021;5(Suppl 2):93 (Correction in 5:115). PMID: 34637030.
- Marshall DA, Jin X, Pittman LB, Smith CJ. The use of patient-reported outcome measures in hip and knee arthroplasty in Alberta. J Patient Rep Outcomes 2021;5(Suppl 2):87. PMID: 34636973.
- Churchill K, Warner L, Keogh E, Al Sayah F. Implementation of EQ-5D-5L as a routine outcome measure in Community Outpatient and Specialized Rehabilitation Services. J Patient Rep Outcomes 2021;5(Suppl 2):103. PMID: 34637018.
- Brower K, Schmitt-Boshnick M, Haener M, Wilks S, Soprovich A. The use of patient-reported outcome measures in primary care: applications, benefits and challenges. J Patient Rep Outcomes 2021;5(Suppl 2):84. PMID: 34636988.
2020
- Zhao H, McClure NS, Johnson JA, Soprovich A, Al Sayah F, Eurich DT. A longitudinal study on the association between diabetic foot disease and health-related quality of life in people with type 2 diabetes. Can J Diabet 2020:44(3);280-286. PMID: 31669187.
- Thomas S, Johnson J, Xie F. 3125 steps to perfect health: A nonparametric approach to developing the EQ-5D-5L value set. Qual Life Research 2020:29(11);3109-3118. PMID: 32705459.
- Johnson JA, Al Sayah F, Buzinski R, Corradetti B, Davison SN, Elliott MJ, Klarenbach S, Manns B, Schick-Makaroff K, Short H, Thomas C, Walsh M. A cluster randomized controlled trial for the Evaluation of routinely Measured PATient reported outcomes in HemodialYsis care (EMPATHY): A study protocol. BMC Health Services Research 2020:20(1):731. PMID: 32778102.
2019
- Jin X, Al Sayah F, Ohinmaa A, Marshall D, Johnson JA. Responsiveness of the EQ-5D-5L and EQ-5D-3L in patients following total hip or knee replacement. Quality of Life Research, 2019; 28(9):2409-2417.
- Zhao H, McClure NS, Johnson JA, Soprovich A, Al Sayah F, Eurich DT. A longitudinal study on the association between diabetic foot disease and health related quality of life in people with type 2 diabetes. Canadian Journal of Diabetes 2019 (forthcoming).
- Tawiah A, Al Sayah F, Ohinmaa A, Johnson JA. Discriminative validity of the EQ-5D-5L and SF-12 in older adults with arthritis. Health and Quality of Life Outcomes 2019; 17:68.
- Jin X, Al Sayah F, Ohinmaa A, Marshall D, Smith C, Johnson JA. The EQ-5D-5L is Superior to the -3L Version in Measuring Health-related Quality of Life in Patients Awaiting Hip or Knee Arthroplasty. Clinical Orthopaedics and Related Research, 2019; 477(7): 1632-1644.
- Soprovich A, Ingstrup M, & Eurich D. The frequency and availability of population-specific patient reported outcome measures and minimal clinically important differences among approved drugs in Canada.Health and Quality of Life Outcomes 2019. 17:4.
- Kashem T, Al Sayah F, Tawiah A, Ohinmaa A, Johnson JA. The Relationship between Individual-Level Deprivation and Health-Related Quality of Life. Health and Quality of Life Outcomes 2019;17(1);176. PMID: 31783859.
2018
- Al Sayah F, Ohinmaa A, Johnson JA. Screening for anxiety and depressive symptoms in type 2 diabetes using patient-reported outcome measures: Comparative performance of the EQ-5D-5L and SF-12v2. MDM Policy and Practice 2018; doi.org/10.1177/2381468318799361.
- Al Sayah F, Yeung RO, Johnson JA. Association of Depressive Symptoms and Diabetes Distress With Severe Hypoglycemia in Adults With Type 2 Diabetes. Can J Diabetes. 2019 Jul;43(5):316-321. doi: 10.1016/j.jcjd.2018.11.002. Epub 2018 Nov 14.
- Short H, Al Sayah F, Ohinmaa A, Johnson JA. The relationship of neighborhood-level material and social deprivation with health-related quality of life. Quality of life Research 2018; 27(12):3265-3274.
- Zhao H, Johnson JA, Al Sayah F, Soprovich A, Eurich D. The association of self-efficacy and hospitalization rates in people with type-2 diabetes: a prospective cohort study. Diabetes Research and Clinical Practice 2018; 143:113-119.
- McClure N, Al Sayah F, Ohinmaa, Johnson JA. Minimally Important Difference of the EQ-5D-5L in Adults with Type 2 Diabetes. Value in Health2018; 21(9):1090-1097.
- Crick K, Al Sayah F, Ohinmaa A, Johnson JA. Responsiveness of the anxiety/depression dimension of the 3- and 5-level versions of the EQ-5D in assessing mental health. Quality of life Research 2018; 27(6):1625-1633.
2017
- Al Sayah F, Ohinmaa A, Johnson JA. Screening for anxiety and depressive symptoms in type 2 diabetes using patient-reported outcome measures: Comparative performance of the EQ-5D-5L and SF-12v2. MDM Policy and Practice 2018; doi.org/10.1177/2381468318799361.
- Al Sayah F, Yeung RO, Johnson JA. Association of Depressive Symptoms and Diabetes Distress With Severe Hypoglycemia in Adults With Type 2 Diabetes. Can J Diabetes. 2019 Jul;43(5):316-321. doi: 10.1016/j.jcjd.2018.11.002. Epub 2018 Nov 14.
- Short H, Al Sayah F, Ohinmaa A, Johnson JA. The relationship of neighborhood-level material and social deprivation with health-related quality of life. Quality of life Research 2018; 27(12):3265-3274.
- Zhao H, Johnson JA, Al Sayah F, Soprovich A, Eurich D. The association of self-efficacy and hospitalization rates in people with type-2 diabetes: a prospective cohort study. Diabetes Research and Clinical Practice 2018; 143:113-119.
- McClure N, Al Sayah F, Ohinmaa, Johnson JA. Minimally Important Difference of the EQ-5D-5L in Adults with Type 2 Diabetes. Value in Health2018; 21(9):1090-1097.
- Crick K, Al Sayah F, Ohinmaa A, Johnson JA. Responsiveness of the anxiety/depression dimension of the 3- and 5-level versions of the EQ-5D in assessing mental health. Quality of life Research 2018; 27(6):1625-1633.
2016
- Al Sayah F, Bansback N, Bryan S, Ohinmaa A, Pullenayegum E, Poissant L, Xie F, Johnson JA. Determinants of Health Preferences in the Canadian EQ-5D-5L Valuation Study. Quality of life Research 2016 Jul;25(7):1679-85.
- Al Sayah F, Qiu W, Johnson JA. Health literacy and health related quality of life in adults with type 2 diabetes: A longitudinal study. Quality of life Research 2016, 25(6):1487-94.
- Al Sayah F, Mladenovic A, Gaebel K, Xie F, Johnson JA. How dead is dead? Qualitative findings from participants of combined traditional and lead-time time trade-off valuations. Quality of life Research 2016, 25(1):35-4
Conference Presentations
2022
- Soprovich A. Selecting patient-reported outcome measures (PROMs). Family Medicine Forum 2022. Toronto, Ontario. November 8-12, 2022.
- Soprovich A. Selecting appropriate patient-reported outcomes (PROMs) for your research. North American Primary Care Research Group (NAPCRG) 50th Annual Conference. Phoenix, Arizona. November 18-22, 2022.
- Soprovich A. Overcoming common challenges to using patient-reported outcome measures (PROMs) in primary care. North American Primary Care Research Group (NAPCRG) 50th Annual Conference. Phoenix, Arizona. November 18-22, 2022.
- Schick-Makaroff K, Wozniak L, Short H, Davison SN, Klarenbach S, Buzinski R, Walsh M, Johnson JA. How the routine use of PROMs for hemodialysis care influences patient-clinician communication: a mixed methods study. 54th Canadian Society of Nephrology (CSN) Virtual Annual General Meeting, May 12-14, 2022.
- Wen J, Al Sayah F, Simon R, Lahtinen M, Johnson JA, Ohinmaa A. A longitudinal analysis on health-related quality of life during the COVID-19 pandemic in Alberta, Canada. 2nd EuroQol Early Career Researchers Meeting, Apr 20, 2022.
2021
- Le CY, Troung LK, Holt CJ, Filbay SR, Dennett L, Johnson JA, Emery CA, Whittaker JL. Measuring Health-Related Quality of Like in Active Youth: A Systematic Review. World Physiotherapy Congress, Virtual Event, April 9-11, 2021.
- Le CY, Truong LK, Holt CJ, Filbay SR, Dennett L, Johnson JA, Emery CA, Whittaker JL. The search for the holy grail: a systematic review of health-related quality of life measures for active youth. Canadian Physiotherapy Association Congress2021, Virtual Event, May 14, 2021.
- Schick-Makaroff K, Wozniak L, Davison SN, Klarenbach S, Buzinski R, Walsh M, Johnson JA. How the routine use of PROMs for hemodialysis care influences patient-clinician communication: a mixed methods study. 28th Annual Conference of the International Society for Quality of Life Research. Qual Life Res 2021;30(Suppl 1):3102:S132. https://doi.org/10.1007/s11136-021-02976-1
- Al Sayah F, Lahtinen M, Simon R, Higgens B, Ohinmaa A, Johnson JA. The Impact of COVID-19 pandemic on health-related quality of life of adults visiting emergency departments and primary care clinics in Alberta. EuroQol Academy Meeting, March 1, 2021.
- Soprovich A. Selecting appropriate patient-reported outcomes (PROMs) for your research. North American Primary Care Research Group (NAPCRG) 49th Annual Meeting. November 19-23, 2021.
2020
- Soprovich, AL, & Al Sayah, F. Using patient-reported outcomes (PROs) in your clinical practice. The College of Family Physicians of Canada, Family Medicine Forum. November 4-7, 2020.
- Soprovich, AL, Brower, K., & Schmitt-Boshnick, M. Illuminating patient voices: Using patient-reported outcome measures (PROMs) at multiple levels. North American Primary Care Research Group (NAPCRG) 48th Annual Meeting. November 20-24, 2020.
- Schick-Makaroff K, Wozniak L, Short H, Davison S, Klarenbach S, Buzinski R, Johnson J. Burden of mental health symptoms and perceptions of their management in hemodialysis care: a mixed methods study. [Poster Presentation] 27th Virtual Annual Conference of the International Society for Quality of Life Research (ISOQOL), October 19-23, 2020. Qual Life Res 2020;29(Suppl 1):S49.
- Al Sayah F, Lahtinen M, Bonsel G, Ohinmaa A, Johnson JA. A multi-level approach for the use of routinely collected patient-reported outcome measures (PROMs) data in health systems. 27th Virtual Annual Conference of the International Society for Quality of Life Research (ISOQOL), October 19-23, 2020. Qual Life Res 2020;29(Suppl 1):S194.
- Al Sayah F, Churchill K, Warner L. Using routinely collected patient-reported outcome measures (PROMs) data in evaluating community rehabilitation services in Alberta, Canada. Virtual ISOQOL 27th Annual Conference, Oct 19-23, 2020.
- Jin X, McClure NS, Al Sayah F, Ohinmaa A, Johnson JA. Minimally Important Differences for EQ-5D instruments: A Systematic Review of Estimates in Published Literature. [Poster Presentation] 4th EuroQol Academy Meeting 2020, Prague, Czech Republic, March 3, 2020.
- McClure NS, Xie F, Johnson JA. Unpacking small differences in the EQ-5D-5L health utility scores: Are you better, worse or the same? [Poster Presentation] 4th EuroQol Academy Meeting 2020, Prague, Czech Republic, March 3, 2020.
- Wen J, Jin X, Al Sayah F, Short H, Ohinmaa A, Johnson JA. Mapping the Modified Edmonton Symptom Assessment System – Renal onto EQ-5D-5L in patients with chronic kidney disease. [Poster Presentation] 1st EuroQol Early Career Researchers Meeting 2020, Prague, Czech Republic, March 1, 2020.
- Jin X, Al Sayah F, Ohinmaa A, Johnson JA. Estimating minimally important difference of the EQ-5D-3L and -5L in patients following total hip or knee replacement: An exploratory analysis of a novel approach using the misery index. [Poster Presentation] 1st EuroQol Early Career Researchers Meeting 2020, Prague, Czech Republic, March 1, 2020.
2019
- Ilkiw N and Short H. EMPATHY Initiative [Oral Presentation]. 2019 Alberta Kidney Days, March 15, 2019, Calgary, Alberta.
- Jin X, McClure NS, Le CY, Baghbaninaghadehi F, Al Sayah F, Ohinmaa A, Johnson JA. Minimally Important Differences for EQ-5D instruments: A Systematic Review of Estimates in Published Literature. CADTH Symposium, April 14-16, 2019, Edmonton AB.
- McClure NS, Xie F, Johnson JA. Individual and public preferences for health states: what can be learned from ties in EQ-5D-5L time-trade-off valuation studies? [Poster Presentation] 2019 Canadian Agency for Drugs and Technologies in Health Symposium, Edmonton, AB, April 14, 2019.
- Johnson JA, Buzinski R, Corradetti B, Davison S, Duperron P, Klarenbach S, Manns B, Short H, Thomas C, Walsh M. Evaluation of routinely Measured PATient reported outcomes in HemodialYsis care (EMPATHY): Implementing a cluster randomized controlled trial at the health system level. CAHSPR 2019, Halifax NS, May 29-31, 2019.
- Wen J, Jin X, Ohinmaa A. Economic Evaluation of Sucrose Octasulfate Dressing for the Treatment of Diabetic Foot Ulcer in Canada. 11th Huaxia Pharmacoeconomics and HTA Forum, Nanjing, China, June 29-30, 2019.
- Al Sayah F, Lubetkin E, Rey Ares L, Derrett S. A Systematic Review on EQ-5D and Health Inequalities – Preliminary Results. 36th EuroQol Plenary meeting, September 18- 21, 2019, Brussels, Belgium.
- Jin X, Al Sayah F, Ohinmaa A, Marshall DA, Johnson JA. What is behind the “mobility” dimension of the EQ-5D? An exploratory analysis in patients following total hip/knee replacement. 36th EuroQol Plenary meeting, September 18- 21, 2019, Brussels, Belgium.
2018
- Jin X, Al Sayah F, Ohinmaa A, Marshall D, Smith C, Johnson JA. EQ-5D-5L vs. EQ-5D-3L: A cross-sectional comparison of measurement properties among total hip and knee replacement patients. [Poster Presentation] 3rd EuroQol Academy Meeting, Budapest Mar 6-8, 2018.
- Al Sayah F, Ohinmaa A, Johnson JA. Can the EQ-5D-3L predict post-hospitalization healthcare use and outcomes? [Poster Presentation] 3rd EuroQol Academy Meeting, Budapest Mar 6-8, 2018.
- Belag A, Al Sayah F, Yeung RO. Diabetes knowledge, self-care behaviours, and metabolic control in Arabic speaking adults with Type 2 diabetes in Edmonton. [oral presentation] Alberta SPOR SUPPORT unit Summer Institute, May 14-16, 2018.
- Belag A, Al Sayah F, Yeung RO. Diabetes knowledge, self-care behaviours, and metabolic control in Arabic speaking adults with Type 2 diabetes in Edmonton. [poster presentation] Faculty of Medicine and Dentistry Research Day, University of Alberta, May 23, 2018.
- Al Sayah F, Janssen MF, Short H, McClure NS, Ohinmaa A, Johnson JA. The Use of EQ-5D in Vulnerable Populations: A Systematic Review of the Literature. [poster presentation] 35th EuroQol Plenary meeting, Lisbon, Portugal, September 19-22, 2018.
- Lubetkin E, Derrett S, Al Sayah F, Janssen MF, Bonsel G. Convening a health inequalities special interest group and results from a survey of EuroQol Group members. [poster presentation] 35th EuroQol Plenary meeting, Lisbon, Portugal, September 19-22, 2018.
- Jin X, Al Sayah F, Ohinmaa A, Marshall D, Johnson JA. Responsiveness of the EQ-5D-5L and EQ-5D-3L in patients following total hip or knee replacement. [paper presentation] 35th EuroQol Plenary meeting, Lisbon, Portugal, September 19-22, 2018.
- Al Sayah, F, Janssen B, Short H, McClure B, Ohinmaa A, Johnson JA. The Use of EQ-5D in Vulnerable Populations: A Systematic Review of the Literature [Poster Presentation]. ISOQOL25th Annual Conference, October 24-27, 2018, Dublin, Ireland.
- Al Sayah F, Ohinmaa A, Johnson JA. Can the EQ-5D-3L predict post-hospitalization healthcare use and outcomes? [Poster presentation] ISPOR Europe, Nov 10-14, Barcelona, Spain. Value in Health 2018, 21 (S3); PMU92.
- Kashem T, Al Sayah F, Ohinmaa A, Johnson JA. The relationship between individual-level deprivation with health-related quality of life in the general population. ISPOR Europe, Nov 10-14, Barcelona, Spain. Value in Health 2018, 21 (S3); PMU123.
- Tawiah A, Al Sayah F, Ohinmaa A, Johnson JA. Discriminative validity of the EQ-5D-5L and SF-12 in older adults with arthritis. ISPOR Europe, Nov 10-14, Barcelona, Spain. Value in Health 2018, 21 (S3); PRM173.
- Jin X, Al Sayah F, Ohinmaa A, Marshall D, Johnson JA. EQ-5D-3L vs. EQ-5D-5L: A cross-sectional comparison of measurement properties among total hip and knee replacement patients. Value in Health 2018, 21 (S3); PRM175.
- Jin X, Al Sayah F, Ohinmaa A, Marshall D, Johnson JA. Responsiveness of the EQ-5D-5L and EQ-5D-3L in patients following total hip or knee replacement. Value in Health 2018, 21 (S3); PRM169.
2017
- Crick K, Al Sayah F, Ohinmaa A, Johnson JA. How well do the EQ-5D-3L and 5L perform in assessing changes in mental health? [Podium presentation] International Society for Pharmacoeconomics and Outcomes Research, 22nd Annual International Meeting, May 20-24, 2017. Value in Health 2017; 20 (5): A12-A13.
- Al Sayah F, Ohinmaa A, Johnson JA. How well does the EQ-5D-5L screen for mental health compared to the SF-12? [Poster presentation] International Society for Pharmacoeconomics and Outcomes Research, 22nd Annual International Meeting, May 20-24, 2017.
- McClure NS, Al Sayah F, Ohinmaa A, Johnson JA. Minimally Important Difference of the EQ-5D-5L in Adults with Type 2 Diabetes. [Poster Presentation] International Society for Pharmacoeconomics and Outcomes Research, 22nd Annual International Meeting, May 20-24, 2017.
- Crick K, Al Sayah F, Ohinmaa A, Johnson JA. How well do the EQ-5D-3L and 5L perform in assessing changes in mental health? [Podium presentation] International Society for Pharmacoeconomics and Outcomes Research, 22nd Annual International Meeting, May 20-24, 2017.
- McClure NS, Al Sayah F, Johnson JA. Interpretation of health-related quality of life scores using estimates of the minimally important difference. [Poster presentation] Summer Institute 2017, A Spotlight on Patient-Oriented Research, Edmonton, AB, June 26, 2017.
- Short H, Al Sayah F, Ohinmaa A, Johnson JA. The relationship of material and social deprivation with health status. [Poster Presentation] 34th EuroQol Plenary Meeting, Barcelona Sept 19-21, 2017.
- Herdman M, Al Sayah F, Ohinmaa A, Mott D, Devlin N, Johnson JA. Workshop to discuss the legitimacy, estimation and uses of the minimal important difference (MID) with EQ-5D. EuroQol Plenary Meeting, Barcelona, Spain Sept 21-23, 2017.
- Short H, Al Sayah F, Ohinmaa A, Johnson J.A. The relationship of material and social deprivation with health status. [Poster presentation] 24th Annual Conference of the International Society for Quality of Life Research, October 18-21, 2017, Philadelphia, United States. Quality of Life Research 2017; 26: Suppl. 1:(A2064):109.
- Huffman S, Al Sayah F, Ohinmaa A, Johnson J.A. What does the “usual activities” dimension of the EQ-5D measure? [Poster presentation] 24th Annual Conference of the International Society for Quality of Life Research, October 18-21, 2017, Philadelphia, United States. Quality of Life Research 2017; 26: Suppl. 1:(A2035):90.
- Al Sayah F, Leischner R, Oddie S, Makin A, Ohinmaa A, Johnson J.A. Putting Patients at the Centre of Health Care: The use of PROMs in Primary Care Networks [oral presentation: 1 hour workshop]. Accelerating Primary Care Conference, Calgary, AB, Nov 17-18, 2017.
- McClure NS, Al Sayah F, Ohinmaa A, Johnson JA. Minimally important differences for preference-based measures of health-related quality of life: The state of the debate and a look forward. [Discussion paper] Alberta Health Economics Study Group, Edmonton, AB, Nov 21, 2017.
2016
- Al Sayah F, Johnson ST, Vallance JK. The association of health literacy with physical activity and walking in community-dwelling older adults. [Poster Presentation] The Society of Behavioral Medicine Annual Meeting. Washington, DC, April 2016.
- Al Sayah F, Johnson JA, Ohinmaa A, Xie F, Bansback N. Health literacy and logical inconsistencies in health state valuations: Results from the Canadian EQ-5D-5L valuation study. [Poster Presentation] 33rd EuroQol Plenary Meeting, Berlin Sept 15-17, 2016.
- Al Sayah F, Johnson JA, Ohinmaa A, Xie F, Bansback N. Health literacy and logical inconsistencies in health state valuations: Results from the Canadian EQ-5D-5L valuation study. [Oral Presentation] ISOQOL 23rd Annual Conference, Copenhagen, Denmark, October 19-22, 2016. Quality of Life Research 2016:25(Suppl 1):24(A102.4).
- McClure N, Al Sayah F, Ohinmaa A, Johnson JA. Minimally Important Difference of the EQ-5D-5L in Adults with Type 2 Diabetes. [Poster Presentation] ISOQOL 23rd Annual Conference, Copenhagen, Denmark, October 19-22, 2016. Quality of Life Research 2016:25(Suppl 1):133(A2107).
- Nagase FN, Al Sayah F, Ohinmaa A, Johnson JA. Health-related quality of life of adults with type 2 diabetes reporting diabetic foot disease. ISOQOL 23rd Annual Conference, Copenhagen, Denmark, October 19-22, 2016. Quality of Life Research 2016:25 (Suppl 1):133(A2109).
- Al Sayah F, Johnson JA, Ohinmaa A. The performance of EQ-5D-5L and VR-12 in Assessing Mental Health. [Poster Presentation] ISOQOL 23rd Annual Conference, Copenhagen, Denmark, October 19-22, 2016. Quality of Life Research 2016:25(Suppl 1):94(A1018)
- Al Sayah F, Qiu W, Xie F, Johnson JA. Comparative Performance of the EQ-5D-5L and SF-6D in Adults with Type 2 Diabetes. [Poster Presentation] ISOQOL 23rd Annual Conference, Copenhagen, Denmark, October 19-22, 2016. Quality of Life Research 2016:25(Suppl 1):132(A2103).
- Al Sayah F, Johnson JA, Ohinmaa A. The performance of EQ-5D-5L and VR-12 in Assessing Mental Health. [Oral Presentation] 38th Annual North American Society for Medical Decision Meeting (SMDM), October 23-26, 2016.
- Al Sayah F, Johnson JA, Ohinmaa A, Xie F, Bansback N. Health literacy and logical inconsistencies in health state valuations: Results from the Canadian EQ-5D-5L valuation study. [Poster Presentation] 38th Annual North American Society for Medical Decision Meeting (SMDM), October 23-26, 2016.
2015
- Wozniak L, Soprovich A, Rees S, Al Sayah F, Majumdar SR, Johnson JA. Contextualizing the Effectiveness of a Collaborative Care Model for Diabetes and Depression in Primary Care: A Qualitative Assessment. [Oral Presentation] CAHSPR Conference 2014, Toronto, ON May 12-15, 2014.
- Johnson JA, Lier D, Soprovich A, Al Sayah F, Qiu W, Majumdar SR. Cost-effectiveness of Nurse-led Collaborative Care For Patients With Diabetes Who Screen Positive For Depression in Primary Care: Results from a controlled implementation trial. [Oral Presentation]. CAHSPR Conference, Montreal, PQ, May 26-28, 2015.
- Agborsangaya C, Al Sayah F, Bansback N, Ohinmaa A, Pullenayegum E, Xie F, Johnson JA. Impact of Health Literacy and Multimorbidity on EQVT Health Valuation: A Secondary Analysis of the Canadian EQ-5D-5L Valuation Study. [Poster Presentation] 31st EuroQol Plenary meeting, Stockholm, Sweden, Sept 25-27, 2014.
- McClure N, Al Sayah F, Xie F, Luo N, Johnson JA. Instrument-defined estimates of minimally important difference in EQ-5D-5L index score for Canadian, Chinese and Spanish scoring algorithms. [Poster Presentation] ISOQOL 22nd Annual Conference, Vancouver, Canada, October 21-24, 2015. Quality of Life Research 2015:24(Suppl 1): 181 (A3038).
- Al Sayah F, Bansback N, Bryan S, Ohinmaa A, Pullenayegum E, Xie F, Johnson JA. Determinants of Health Preferences in the Canadian EQ-5D-5L Valuation Study. [Poster Presentation] ISOQOL 22nd Annual Conference, Vancouver, Canada, October 21-24, 2015. Quality of Life Research 2015:24(Suppl 1): 177 (A3016).
- Al Sayah F, Qiu W, Johnson JA. Health Literacy and Health-Related Quality of Life in Adults with Type 2 Diabetes: A Longitudinal Study. [Poster Presentation] ISOQOL 22nd Annual Conference, Vancouver, Canada, October 21-24, 2015. Quality of Life Research 2015:24(Suppl 1): 103 (A1054).
- Mladenovic AB, Al Sayah F, Qiu W, Johnson JA, Intervention Dose and Health-related Quality of life in a Collaborative Care Intervention for Patients with Type 2 Diabetes and Positive Depressive Symptoms. [Poster Presentation] 14th Symposium of the International Diabetes Epidemiology Group, Vancouver, Canada, Dec 2015.
- Thiel DM, Al Sayah F, Johnson ST, Johnson JA. Relationship between Physical Activity and Health-Related Quality of Life in Alberta’s Type 2 Diabetes Population. [Poster Presentation] 14th Symposium of the International Diabetes Epidemiology Group (IDEG); 2015 Dec 5-6; Vancouver, British Columbia.
Collaborations
APERSU collaborates with researchers from several academic institutions across Canada and internationally:
- Nancy Devlin, Office of Health Economics, UK
- Mike Herdman, Office of Health Economics, UK
- Michael Walsh, McMaster University, Hamilton, Ontario
- Feng Xie, McMaster University, Hamilton, Ontario
- Nan Luo, National University of Singapore, Singapore
- Braden Manns, University of Calgary, Calgary, Alberta
- Nick Bansback, University of British Columbia, Vancouver, British Columbia
- Deborah Marshall, University of Calgary, Calgary, Alberta
- Scott Oddie, AHS and Red Deer College, Red Deer, Alberta
- Bas Janssen, The EuroQol Group, Netherlands
- David Whitehurst, Simon Fraser University, Vancouver, British Columbia
Research Highlights
Xuejing (Jennifer) Jin, Fatima Al Sayah, Arto Ohinmaa, Deborah A. Marshall, Christopher Smith, Jeffrey A. Johnson
Clinical Orthopaedics and Related Research (CORR) July 2019, 477:1632-1644.
The EQ-5D has been widely using in measuring health-related quality of life (HRQL) of patients following joint arthroplasty, especially in registry programs. Previous studies indicated that the ceiling effect of the three-level EQ-5D (EQ-5D-3L) limits its application in joint arthroplasty. The five-level EQ-5D (EQ-5D-5L) was developed by adding two response levels to each dimension to improve measurement properties of the instrument; however, in joint arthroplasty field, evidence that supports the EQ-5D-5L is superior to the 3L version is limited.
In this study, Jin and colleagues examined and compared the performance of the EQ-5D-3L and EQ-5D-5L among patients awaiting total hip (THA) or knee (TKA) arthroplasty using data from the Alberta Bone and Joint Health Data Repository, which recorded information on all patients receiving elective hip or knee replacements in Alberta since 2010.
The study showed that, compared to the 3L version, the EQ-5D-5L had better measurement properties in terms of response distribution, construct validity, and ability to discriminate between patients with different severity levels of health problems, especially in mobility (a key health aspect or outcome in these patients).
Jin concluded, “the EQ-5D-5L is more appropriate for measuring HRQL of patients awaiting THA and TKA than the EQ-5D-3L.” The findings “support the use of the EQ-5D-5L for more accurate measurement of HRQL in clinical research and routine application among these patients.”
You can read the full article here.
Following the publication, the Clinical Orthopaedics and Related Research journal published a commentary that summarized the importance and limitations of collecting patient-reported outcome measures (PROMs) in hip and knee replacement. The commentary endorsed the application of the EQ-5D in economic evaluations of hip and knee interventions, and highlighted the demand of minimally important difference (MID) in this field. Additionally, it recommended establishing public searchable databases, and exploring the use of pre-surgery PROMs to screen patients or predict prognosis.
You can read the full commentary here.
For any questions or comments, please do not hesitate to contact us at apersu@ualberta.ca.
Fatima Al Sayah, Arto Ohinmaa, Jeffrey A. Johnson
MDM Policy and Practice 2018 (in press)
Anxiety and depressive symptoms are highly prevalent in chronic disease patients, including those with type 2 diabetes. These symptoms, often undiagnosed and untreated, adversely impact diabetes management and outcomes.
In this study, Al Sayah and colleagues examined the performance of two of the most commonly used patient-reported outcome (PRO)measures of health-related quality of life (EQ-5D-5L and the SF-12 v.2) in screening for anxiety and depressive symptoms in type 2 diabetes patients in primary care setting in Alberta. The researchers opted to explore these measures given their increasing use in the healthcare system in routine outcome measurement.
The researchers found that the EQ-5D-5L and the SF-12 to be suitable tools for screening for anxiety and depressive symptoms in adults with type 2 diabetes. The anxiety/depression dimension of the EQ-5D and the MCS score of the SF-12 had the best performance in screening for these symptoms.
Al Sayah stated “These tools present a unique opportunity for a standardized approach for routine mental health screening in primary care settings within the context of routine outcome measurement initiatives, particularly for patients with chronic diseases”. And added “Users should consider all pros and cons of each measure while selecting a PRO measure that would also serve as a screener for mental health”.
You can read the full article here: https://journals.sagepub.com/doi/full/10.1177/2381468318799361
For any questions or comments, please do not hesitate to contact us at apersu@ualberta.ca